SHANK1/SHANK3 Antibody: PerCP

Biorbyt

SHANK1/SHANK3 antibody

16

1 microg/ml of SMC-460 was sufficient for detection of SHANK1/SHANK3 in 20 microg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry

WB (1:1000), ICC/IF (1:100) ELISA, ICC, IF, IHC, WB

Research Use Only

Monoclonal

N367/51 (Formerly sold as S367-51)

1 mg/ml

PerCP

Shank3

SH3 and multiple ankyrin repeat domains 3

proline-rich synapse-associated protein 2; Prosap2; SH3 and multiple ankyrin repeat domains protein 3; SH3/ankyrin domain gene 3; Shank postsynaptic density protein 3a; Spank-2

Mouse

IgG2a

SH3 and multiple ankyrin repeat domains protein 3

Mouse monoclonal to SHANK1 (PerCP). SHANK proteins are scaffolding adaptors that have been shown to integrate neurotransmitter receptors into the cortical cytoskeleton at postsynaptic densities. SHANK1-3 of the SHANK/ProSAP family are molecular scaffolds in the postsynaptic density (PSD). SHANK recruits betaPIX and PAK to dendritic spines to regulate postsynaptic structure and interacts with ionotropic receptor and metabotropic glutamate receptor complexes. Transcript splice variation in the Shank family influences the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain to ensure normal development..

Human, Mouse, Rat

See Manual

12352203