Sheep anti Human Glypican-3 (GPC3)
X2395P
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
Overview
- SupplierNordic-MUbio
- Product NameSheep anti Human Glypican-3 (GPC3)
- Delivery Days Customer7
- ApplicationsWestern Blot, ImmunoHistoChemistry
- Applications SupplierImmunohistochemistry (paraffin);Western Blotting;Immunohistochemistry (paraffin)
- Category SupplierPrimary antibodies
- CertificationResearch Use Only
- ConcentrationSee vial for concentration
- HostSheep
- IsotypeIgG
- Scientific DescriptionGPC3, GPC-3, OCI5, OCI-5, GTR2-2, MXR7
- Shelf life instructionSee expiration date on vial
- ReactivityHuman
- Reactivity SupplierHuman
- Reactivity Supplier NoteC terminal recombinant protein (~70aa) which does not overlap with clone 1G12 epitope)
- Storage InstructionProduct should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles
- UNSPSC12352203
References
- 1. Lai, J.P., et al. Sulfatase 2 up-regulates glypican 3, promotes fibroblast growth factor signaling, and decreases survival in hepatocellular carcinoma. Hepatology 2008, 47, 1211-1222. 2. Zynger, D.L., et al. Expression of glypican 3 in ovarian and extragonadal germ cell tumors. Am. J. Clin. Pathol. 2008, 130, 224-230. 3. Anatelli, F., et al. Value of glypican 3 immunostaining in the diagnosis of hepatocellular carcinoma on needle biopsy. Am. J. Clin. Pathol. 2008, 130, 219-223. 4. Yamanaka, K., et al. Immunohistochemical study of glypican 3 in thyroid cancer. Oncology 2007, 73, 389-394. 5. Filmus, J., et al. Glypicans. Genome Biol. 2008, 9, 224. 6. Baumhoer, D., et al. Glypican 3 expression in human nonneoplastic, preneoplastic, and neoplastic tissues: a tissue microarray analysis of 4,387 tissue samples. Am. J. Clin. Pathol. 2008, 129, 899-906. 7. Capurro, M.I., et al. Glypican-3 inhibits Hedgehog signaling during development by competing with patched for Hedgehog binding. Dev. Cell 2008, 14, 700-711. 8. Motomura, Y., et al. HLA-A2 and -A24-restricted glypican-3-derived peptide vaccine induces specific CTLs: preclinical study using mice. Int. J. Oncol. 2008, 32, 985-990. 9. Cheng, W., et al. Glypican-3-mediated oncogenesis involves the Insulin-like growth factor-signaling pathway. Carcinogenesis 2008, 29, 1319-1326.