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Chemical Structure
Chemical Structure
Chemical Structure

Shogaol [555-66-8]

Research Use Only
CDX-S0279
Chemodex
CAS Number555-66-8
Product group Chemicals
Estimated Purity>98%
Molecular Weight276.37
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Overview

  • Supplier
    Chemodex
  • Product Name
    Shogaol [555-66-8]
  • Delivery Days Customer
    10
  • CAS Number
    555-66-8
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Formulation
    Liquid
  • Hazard Information
    Warning
  • Molecular Formula
    C17H24O3
  • Molecular Weight
    276.37
  • Scientific Description
    Chemical. CAS: 555-66-8. Formula: C17H24O3. MW: 276.37. Shogaol is a pungent bioactive component of ginger (Zingiber officinale Roscoe) with anti-inflammatory, anticancer, antioxidant, neuroprotective, antidiabetic, cardioprotective and antimicrobial properties. The anticancer activity is associated with the induction of apoptosis in cancer cells through the production of reactive oxygen species and the activation of caspase, impairment of tubulin polymerization, downregulation of STAT3 and NF-kappaB signaling, inhibition of the expression of inflammatory mediators and suppresseion of Toll-like receptor signaling. It also has been shown to induce autophagy and activate peroxisomal proliferator activated receptor gamma (PPARgamma). 6-Shogaol can also activate both TRPV1 and TRPA1 channels. 6-Shogaol inhibits the NF-kappaB and NLRP3 signaling pathways. - Shogaol is a pungent bioactive component of ginger (Zingiber officinale Roscoe) with anti-inflammatory, anticancer, antioxidant, neuroprotective, antidiabetic, cardioprotective and antimicrobial properties. The anticancer activity is associated with the induction of apoptosis in cancer cells through the production of reactive oxygen species and the activation of caspase, impairment of tubulin polymerization, downregulation of STAT3 and NF-kappaB signaling, inhibition of the expression of inflammatory mediators and suppresseion of Toll-like receptor signaling. It also has been shown to induce autophagy and activate peroxisomal proliferator activated receptor gamma (PPARgamma). 6-Shogaol can also activate both TRPV1 and TRPA1 channels. 6-Shogaol inhibits the NF-kappaB and NLRP3 signaling pathways.
  • SMILES
    OC1=CC=C(CCC(/C=C/CCCCC)=O)C=C1OC
  • Storage Instruction
    2°C to 8°C,RT
  • UNSPSC
    12352200