SHP1-IN-1

MedChem Express

SHP1-IN-1

14

Research Use Only

C22H23N5O4

421.45

SHP1-IN-1 (compound 5p) is a fluorescent probe for the protein tyrosine phosphatase SHP1 containing the Src homology 2 domain. SHP1-IN-1 has SHP1 inhibitory activity, selectivity for Fe3+ ions and good fluorescence properties. SHP1-IN-1 exhibits aggregation post-quenching (ACQ) effect, good interference immunity and low detection limit (5.55 microM)[1].

COC1=CC=CC(C2=NC3=NC(C4=CC=C(C(C(O)=O)=C4)O)=C(N3N2)NC(C)(C)C)=C1

41116134