SHP2-D26 [2458219-65-1]

TargetMol Chemicals

SHP2-D26 [2458219-65-1]

999

2458219-65-1

Chemical

Research Use Only

SHP2-D26

C56H79ClN12O6S2

1115.9

SHP2-D26 is a highly potent and effective SHP2 degrader. Its mechanism of action involves the induction of SHP2 degradation through binding to VHL-1 and SHP2 proteins. Additionally, the degradation of SHP2 induced by SHP2-D26 is dependent on neddylation and proteasome activity.

3 years

C[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)CCCCCCCCN1CCN(CC1)C(=O)CCC(=O)Nc1cccc(Sc2ncc(nc2N)N2CCC(C)(N)CC2)c1Cl)C(C)(C)C)c1ccc(cc1)-c1scnc1C - @@:61 -

-20°C

12352200