SHP2-IN-9

TargetMol Chemicals

SHP2-IN-9

14

Chemical

Research Use Only

SHP2-IN-9

C20H20FN3O2S

385.46

SHP2-IN-9 is a potent inhibitor (IC50 = 1.174 microM) specifically targeting the SHP2 protein, displaying improved penetration across the blood-brain barrier. It exhibits a remarkable 85-fold selectivity for SHP2 over SHP1. By inhibiting SHP2-mediated cell signal transduction and impairing cancer cell proliferation, SHP2-IN-9 effectively suppresses the growth of both cervix cancer tumors and glioblastoma in vivo [1].

3 years

-20°C

51202000