SIAH1 antibody

GeneTex

SIAH1 antibody

9

Knockdown/Knockout validation was supported by references (PMID:35705526)

WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

SIAH1

siah E3 ubiquitin protein ligase 1

BURHAS; E3 ubiquitin-protein ligase SIAH1; RING-type E3 ubiquitin transferase SIAH1; seven in absentia homolog 1; SIAH1A; siah-1a

Rabbit

IgG

E3 ubiquitin-protein ligase SIAH1

This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinsons disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq]

Human

-20°C or -80°C,2°C to 8°C

12352203