SIGLEC8 Polyclonal Antibody

Reddot Biotech

SIGLEC8 Polyclonal Antibody

5

Western Blot

Research Use Only

1 mg/ml

Unconjugated

SIGLEC8

sialic acid binding Ig like lectin 8

CDw329; SAF2; SAF-2; sialic acid-binding Ig-like lectin 8; sialoadhesin family member 2; SIGLEC-8; SIGLEC8L

Rabbit

IgG

Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs, are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule that mediates an association with SLAM-associated protein .

Human, Mouse, Rat

-20°C

12352203