Silodosin (Standard) [160970-54-7]

MedChem Express

Silodosin (Standard) [160970-54-7]

5

160970-54-7

Research Use Only

C25H32F3N3O4

495.53

Silodosin (Standard) is the analytical standard of Silodosin. This product is intended for research and analytical applications. Silodosin (KAD 3213; KMD 3213) is a potent, selective and orally active alpha1A-adrenergic receptor (alpha1A-AR) blocker. Silodosin exhibits high affinity for alpha1A-AR (Ki=0.036 nM), over 162-fold and 50-fold than for alpha1B-AR and alpha1D-AR with Ki values of 21 nM and 2.0 nM, respectively. Silodosin is an effective and well-tolerated agent, it can be used for the investigation of LUTS/BPH[1][3].

O=C(N)C1=CC(C[C@@H](C)NCCOC2=CC=CC=C2OCC(F)(F)F)=CC3=C1N(CC3)CCCO

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