Simeprevir(TMC-435)

Biorbyt

Simeprevir(TMC-435) [923604-59-5]

16

923604-59-5

Research Use Only

C38H47N5O7S2

749.94

Simeprevir (TMC 435350) is a potent inhibitor of HCV NS3/4A protease (Ki = 0.36 nM) and viral replication (replicon EC50 = 7.8 nM).

COC1=CC=C2C(=CC(C3SC=C(C(C)C)N=3)=NC2=C1C)O[C@H]1C[C@H]2C(N(CCCCC=C[C@@H]3C[C@]3(NC(=O)[C@@H]2C1)C(NS(C1CC1)(=O)=O)=O)C)=O - t:34,&1:22,24,33,35,39 -

12352200