Siramesine
M2592
CAS Number147817-50-3
Product group Chemicals
Estimated Purity>99%
Molecular Weight454.58
Overview
- SupplierAbMole BioScience
- Product NameSiramesine
- Delivery Days Customer9
- CAS Number147817-50-3
- Category SupplierChemical
- CertificationResearch Use Only
- Estimated Purity>99%
- Molecular FormulaC30H31FN2O
- Molecular Weight454.58
- Scientific DescriptionSiramesine (Lu 28-179) is a potent sigma-2 receptor agonist. Siramesine has a subnanomolar affinity for sigma-2 receptors (IC50=0.12 nM) and exhibits a 140-fold selectivity for sigma-2 receptors over sigma-1 receptors (IC50=17 nM). Siramesine triggers cell death through destabilisation of mitochondria, but not lysosomes.
- SMILES1'-[4-[1-(4-fluorophenyl)indol-3-yl]butyl]spiro[1H-2-benzofuran-3,4'-piperidine]
- UNSPSC12352200
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