SIRP alpha V2 Protein, Human, Recombinant (aa 31-369, His)

TargetMol Chemicals

SIRP alpha V2 Protein, Human, Recombinant (aa 31-369, His)

16

Research Use Only

38 kDa (predicted). Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.

Signal regulatory protein alpha (SIRPalpha) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPalpha acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the dont eat me signal.Cancer cells highly expressed CD47 that activate SIRP alpha and inhibit macrophage-mediated destruction. SIRP alpha V2 Protein, Human, Recombinant (aa 31-369, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 38 kDa and the accession number is AAH26692.1.

-20°C

12352200