SIRT2-IN-11

MedChem Express

SIRT2-IN-11

10

Research Use Only

99.94

C21H22N2O

318.41

SIRT2-IN-11 (AEM1) is a selective SIRT2 inhibitor with an IC 50 value of 18.5 microM. SIRT2-IN-11 p53-dependently induces apoptosis, activates expression of CDKN1A , PUMA and NOXA , and increases acetylation of p53. SIRT2-IN-11 can be used for the research of p53-related cancers [1] .

O=C(C1=CC=C2NC(C3C(C4CCC3C4)C2=C1)C5=CC=CC=C5)N

2°C to 8°C

12352200