SIRT6-IN-2

MedChem Express

SIRT6-IN-2

14

Research Use Only

99.85

C19H14N2O6

366.32

SIRT6-IN-2 (Compound 5) is a selective SIRT6 inhibitor ( IC 50 : 34 microM). SIRT6-IN-2 increases acetylation of H3K9 and increases glucose uptake in cultured cells. SIRT6-IN-2 also reduces T cell proliferation. SIRT6-IN-2 has immunosuppressive and chemosensitizing effects [1] .

O=C(C1=CC=C(NC(C2=CC=CO2)=O)C=C1)NC3=CC(C(O)=O)=C(O)C=C3

-20°C,2°C to 8°C

12352200