Sirtinol [410536-97-9]

Kanda T, Sasaki R, Nakamoto S, et al. The sirtuin inhibitor sirtinol inhibits hepatitis A virus (HAV) replication by inhibiting HAV internal ribosomal entry site activity. Biochem Biophys Res Commun. 2015 Oct 23;466(3):567-71. PMID: 26388050. Lee M, Kim DW, Yoon H, et al. Sirtuin 1 attenuates nasal polypogenesis by suppressing epithelial-to-mesenchymal transition. J Allergy Clin Immunol. 2015 Sep 2. [Epub ahead of print]. PMID: 26342525. Zhang L, Ma R, Hu J, et al. Sirtuin Inhibition Adversely Affects Porcine Oocyte Meiosis. PLoS One. 2015 Jul 15;10(7):e0132941. PMID: 26176547. Gautam R, Akam EA, Astashkin AV, et al. Sirtuin inhibitor sirtinol is an intracellular iron chelator. Chem Commun (Camb). 2015 Mar 25;51(24):5104-7. PMID: 25715179. Tsai YF, Yu HP, Chang WY, et al. Sirtinol inhibits neutrophil elastase activity and attenuates lipopolysaccharide-mediated acute lung injury in mice. Sci Rep. 2015 Feb 10;5:8347. PMID: 25666548. Botti C, Caiafa I, Coppola A, et al. SIRT1 inhibition affects angiogenic properties of human MSCs. Biomed Res Int. 2014;2014:783459. PMID: 25243179. Fong Y, Lin YC, Wu CY, et al. The antiproliferative and apoptotic effects of sirtinol, a sirtuin inhibitor on human lung cancer cells by modulating Akt/bèta-catenin-Foxo3a axis. ScientificWorldJournal. 2014;2014:937051. PMID: 25184156. Back JH, Rezvani HR, Zhu Y, et al. Cancer cell survival following DNA damage-mediated premature senescence is regulated by mammalian target of rapamycin (mTOR)-dependent inhibition of sirtuin 1. J Biol Chem. 2011 May 27;286(21):19100-19108. PMID: 21471201.