SJF620 (hydrochloride)

MedChem Express

SJF620 (hydrochloride)

10

Research Use Only

99.28

C41H45ClN8O7

797.30

SJF620 hydrochloride is a PROTAC connected by ligands for Cereblon and Btk with a DC 50 of 7.9 nM. SJF620 contains a Lenalidomide analog for recruiting CRBN [1] .

O=C(N1)C(CCC1=O)N(C2=O)CC3=C2C=CC(OCCOCCOCCN4CCC(CC4)N5N=C(C6=C(N)N=CN=C65)C7=CC=C(C=C7)OC8=CC=CC=C8)=C3.[H]Cl

-20°C

12352200