SK1- I (hydrochloride)

MedChem Express

SK1- I (hydrochloride) [2366222-05-9]

10

2366222-05-9

Research Use Only

99.49

C17H28ClNO2

313.86

SK1-I hydrochloride (BML-258 hydrochloride), an analog of sphingosine, is an isozyme-specific competitive SPHK1 inhibitor with a K i value of 10 microM [1] . SK1-I hydrochloride shows no activity at SPHK1 PKCalpha, PKCdelta, PKA, AKT1, ERK1, EGFR, CDK2, IKKbeta or CamK2beta. SK1-I hydrochloride enhances autophagy and has antitumor activity [2] .

OC[C@H]([C@H](/C=C/C1=CC=C(C=C1)CCCCC)O)NC.[H]Cl

2°C to 8°C

12352200