SKA3 Antibody, FITC conjugated
CSB-PA816899LC01HU
ReactivityHuman
Product group Antibodies
TargetSKA3
Overview
- SupplierCusabio
- Product NameSKA3 Antibody, FITC conjugated
- Delivery Days Customer20
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateFITC
- Gene ID221150
- Target nameSKA3
- Target descriptionspindle and kinetochore associated complex subunit 3
- Target synonymsC13orf3; RAMA1; spindle and kinetochore-associated protein 3
- HostRabbit
- IsotypeIgG
- Protein IDQ8IX90
- Protein NameSpindle and kinetochore-associated protein 3
- Scientific DescriptionComponent of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation (PubMed:19289083, PubMed:19360002, PubMed:23085020). The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies (PubMed:19289083, PubMed:19360002). The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner (PubMed:19289083). In the complex, it mediates the microtubule-stimulated oligomerization (PubMed:19289083). Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules (PubMed:23085020).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203