SKI II

MedChem Express

SKI II [312636-16-1]

10

312636-16-1

Research Use Only

99.78

C15H11ClN2OS

302.78

SKI-II is an oral active and synthetic inhibitor of sphingosine kinase (SK) activity, with IC 50 values of 78 microM and 45 microM for SK1 and for SK2, respectively. SKI II causes an irreversible inhibition of SK1 by inducing its lysosomal and/or proteasomal degradation [1] [2] .

OC1=CC=C(NC2=NC(C3=CC=C(Cl)C=C3)=CS2)C=C1

-20°C,2°C to 8°C

12352200