SLAMF6 Polyclonal Antibody
RD265761A
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetSLAMF6
Overview
- SupplierReddot Biotech
- Product NameSLAMF6 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID114836
- Target nameSLAMF6
- Target descriptionSLAM family member 6
- Target synonymsactivating NK receptor; CD352; KALI; KALIb; Ly108; natural killer-, T- and B-cell antigen; NK-T-B-antigen; NTBA; NTB-A; NTBA receptor; SF2000; SLAM family member 6
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203