Immunohistochemistry of paraffin-embedded Human brain tissue using SLC22A17 Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human brain tissue using SLC22A17 Polyclonal Antibody at dilution 1:40
SLC22A17 Polyclonal Antibody
E-AB-12870
Product group Antibodies
Overview
- SupplierElabscience
- Product NameSLC22A17 Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA IHC
- CertificationResearch Use Only
- Concentration0.3mg/ml
- Scientific DescriptionCell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis.
- UNSPSC12352203