SLC22A2 Antibody, Biotin conjugated

Cusabio

SLC22A2 Antibody, Biotin conjugated

20

ELISA

Research Use Only

Polyclonal

Biotin

SLC22A2

solute carrier family 22 member 2

OCT2; organic cation transporter 2; solute carrier family 22 (organic cation transporter), member 2; solute carrier family 22 member 2

Rabbit

IgG

Solute carrier family 22 member 2

Mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, dopamine, noradrenaline (norepinephrine), serotonin, choline, famotidine, ranitidine, histamin, creatinine, amantadine, memantine, acriflavine, 4-[4-(dimethylamino)-styryl]-N-methylpyridinium ASP, amiloride, metformin, N-1-methylnicotinamide (NMN), tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, cisplatin and oxaliplatin. Cisplatin may develop a nephrotoxic action. Transport of creatinine is inhibited by fluoroquinolones such as DX-619 and LVFX. This transporter is a major determinant of the anticancer activity of oxaliplatin and may contribute to antitumor specificity.

Human

-20°C or -80°C

12352203