SLC22A5 Polyclonal Antibody
RD266347A
ApplicationsImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetSLC22A5
Overview
- SupplierReddot Biotech
- Product NameSLC22A5 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoHistoChemistry
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID6584
- Target nameSLC22A5
- Target descriptionsolute carrier family 22 member 5
- Target synonymsCDSP; high-affinity sodium dependent carnitine cotransporter; OCTN2; organic cation/carnitine transporter 2; solute carrier family 22 member 5
- HostRabbit
- IsotypeIgG
- Scientific DescriptionPolyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy. Alternative splicing of this gene results in multiple transcript variants.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203