Bio-Connect

SLC22A5 Polyclonal Antibody

RD266347A
Reddot Biotech
ApplicationsImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetSLC22A5
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    SLC22A5 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6584
  • Target name
    SLC22A5
  • Target description
    solute carrier family 22 member 5
  • Target synonyms
    CDSP; high-affinity sodium dependent carnitine cotransporter; OCTN2; organic cation/carnitine transporter 2; solute carrier family 22 member 5
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy. Alternative splicing of this gene results in multiple transcript variants.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203