SLC31A1 / CTR1 antibody

GeneTex

SLC31A1 / CTR1 antibody

9

ICC/IF: 1:500. IHC-P: 1:250. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

SLC31A1

solute carrier family 31 member 1

copper transport 1 homolog; copper transporter 1; COPT1; CTR1; high affinity copper uptake protein 1; solute carrier family 31 (copper transporter), member 1; solute carrier family 31 (copper transporters), member 1

Rabbit

IgG

High affinity copper uptake protein 1

Copper is an element essential for life, but excessive copper can be toxic or even lethal to the cell. Therefore, cells have developed sophisticated ways to maintain a critical copper balance, with the intake, export, and intracellular compartmentalization or buffering of copper strictly regulated. The 2 related genes ATP7A (MIM 300011) and ATP7B (MIM 606882), responsible for the human diseases Menkes syndrome (MIM 309400) and Wilson disease (MIM 277900), respectively, are involved in copper export. In S. cerevisiae, the copper uptake genes CTR1, CTR2, and CTR3 have been identified, and in human the CTR1 and CTR2 (MIM 603088) genes have been identified.[supplied by OMIM]

Human, Mouse, Porcine, Rat, Xenopus, Zebra Fish

2°C to 8°C

12352203