
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA145393(SLC7A11 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200)
SLC7A11 Antibody
CSB-PA145393
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
TargetSLC7A11
Overview
- SupplierCusabio
- Product NameSLC7A11 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID23657
- Target nameSLC7A11
- Target descriptionsolute carrier family 7 member 11
- Target synonymsamino acid transport system xc-; calcium channel blocker resistance protein CCBR1; CCBR1; cystine/glutamate transporter; solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11; solute carrier family 7, (cationic amino acid transporter, y+ system) member 11; xCT
- HostRabbit
- IsotypeIgG
- Protein IDQ9UPY5
- Protein NameCystine/glutamate transporter
- Scientific DescriptionThis gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.
- Storage Instruction-20°C or -80°C
- UNSPSC12352203