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SLC7A11-IN-2

Research Use Only
HY-169056
MedChem Express
Molecular Weight356.42
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    SLC7A11-IN-2
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Molecular Formula
    C19H24N4O3
  • Molecular Weight
    356.42
  • Scientific Description
    SLC7A11-IN-2 (Compound 1) is an SLC7A11/xCT inhibitor. SLC7A11-IN-2 induces cell death in HeLa cells by lowering intracellular glutathione levels and increasing oxidative stress, thereby disrupting the oxidative balance within the cells, with an IC50 value of 10.23 microM. Molecular dynamics simulation analysis indicates that SLC7A11-IN-2 has a stronger binding affinity to SLC7A11 compared to Erastin (HY-15763). SLC7A11-IN-2 can be utilized in research within the field of cervical cancer[1].
  • SMILES
    O=C(C(CC(CC)O)C(NNC1=CC=CC=C1)=O)NNC2=CC=CC=C2
  • UNSPSC
    12352200