Bio-Connect
IHC-P analysis of human pancreas tissue using GTX83618 SLC7A8 antibody [5A9]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.
IHC-P analysis of human pancreas tissue using GTX83618 SLC7A8 antibody [5A9]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.
IHC-P analysis of human pancreas tissue using GTX83618 SLC7A8 antibody [5A9]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.

SLC7A8 antibody [5A9]

GTX83618
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetSLC7A8
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    SLC7A8 antibody [5A9] - Overexpression Validated
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:1000. ICC/IF: 1:100. IHC-P: 1:50. FACS: 1:100. IP: 2ug/500ul. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    5A9
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID23428
  • Target name
    SLC7A8
  • Target description
    solute carrier family 7 member 8
  • Target synonyms
    integral membrane protein E16H; large neutral amino acids transporter small subunit 2; LAT2; LPI-PC1; L-type amino acid transporter 2; solute carrier family 7 (amino acid transporter light chain, L system), member 8; solute carrier family 7 (amino acid transporter, L-type), member 8; solute carrier family 7 (cationic amino acid transporter, y+ system), member 8
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDQ9UHI5
  • Protein Name
    Large neutral amino acids transporter small subunit 2
  • Scientific Description
    Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney.
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • LAT2 regulates glutamine-dependent mTOR activation to promote glycolysis and chemoresistance in pancreatic cancer. Feng M et al., 2018 Nov 12, J Exp Clin Cancer Res
    Read more

Related products

Immunohistochemical staining of human pancreas shows moderate membranous positivity in Langerhans cells.
Product group Antibodies
Atlas Antibodies
ApplicationsImmunoHistoChemistry
ReactivityHuman
TargetSLC7A8
  • SizePrice
Product group Antibodies
Boster Bio
ApplicationsWestern Blot, ELISA
TargetSLC7A8
  • SizePrice
IHC-P analysis of kidney carcinoma tissue using GTX83620 SLC7A8 antibody [8B12]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50
Product group Antibodies
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
TargetSLC7A8
  • SizePrice
IP analysis of DDDDK tagged SLC7A8 overexpressed HEK293T lysate using GTX83621 SLC7A8 antibody [4H10].After extensive wash to remove any non-specific binding, the immuno-precipitated products were analyzed with rabbit anti-DDDDK polyclonal antibody. IP reaction : 2microg antibody / 500microl cell lysate
Product group Antibodies
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry
TargetSLC7A8
  • SizePrice
WB analysis of HEK293T (A), HepG2 (B), mouse kidney (C), rat brain (D) whole cell lysates using GTX56211 SLC7A8 antibody.
Product group Antibodies
GeneTex
ApplicationsWestern Blot
TargetSLC7A8
  • SizePrice
Anti-NTAL Antibody
Product group Antibodies
Antibodies.com
ApplicationsWestern Blot, ELISA
  • SizePrice
Product group Antibodies
LifeSpan BioSciences
ApplicationsWestern Blot
TargetSLC7A8
  • SizePrice
Product group Antibodies
RayBiotech
ApplicationsFlow Cytometry, Western Blot
TargetSLC7A8
  • SizePrice
Product group Antibodies
Biosynth
  • SizePrice