SM-324405

MedChem Express

SM-324405 [677773-91-0]

10

677773-91-0

Research Use Only

98.52

C19H23N5O4

385.42

SM-324405 is a TLR7 agonistic antedrug ( EC 50 = 50 nM), with pEC 50 values of 7.3 and 6.6 for human TLR7 and Rat TLR7, respectively. SM-324405 is used for immunoresearch of allergic diseases. An antedrug is defined as a locally active compound that is designed to be rapidly metabolized to an inactive form upon entry into the circulation and prevents systemic toxicity by losing its agonistic activity in a plasmatic environment [1] [2] [3] .

O=C(OC)CC1=CC=CC(CN2C(NC3=C(N)N=C(OCCCC)N=C23)=O)=C1

-20°C,2°C to 8°C

12352200