Western blot analysis of extracts from RAW264.7 cells and 293 cells, using Smad2 (Ab-220) antibody.
Western blot analysis of extracts from RAW264.7 cells and 293 cells, using Smad2 (Ab-220) antibody.
SMAD2 (Ab-220) Antibody
CSB-PA594584
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetSMAD2
Overview
- SupplierCusabio
- Product NameSMAD2 (Ab-220) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID4087
- Target nameSMAD2
- Target descriptionSMAD family member 2
- Target synonymshMAD-2; hSMAD2; JV18; JV18-1; MAD homolog 2; MADH2; MADR2; mother against DPP homolog 2; mothers against decapentaplegic homolog 2; Sma- and Mad-related protein 2; SMAD, mothers against DPP homolog 2
- HostRabbit
- IsotypeIgG
- Protein IDQ15796
- Protein NameMothers against decapentaplegic homolog 2
- Scientific DescriptionReceptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator. Riggins G.J., Nat. Genet. 13:347-349(1996). Zhang Y., Nature 383:168-172(1996). Eppert K., Cell 86:543-552(1996).
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203