Western Blot Positive WB detected in: Hela whole cell lysate, HepG2 whole cell lysate, Jurkat whole cell lysate, K562 whole cell lysate, Mouse heart tissue, Mouse liver tissue, Mouse brain tissue All lanes: SMAD2 antibody at 3ug/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 53, 49 kDa Observed band size: 53 kDa

SMAD2 Antibody

CSB-PA15557A0RB

ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry

Product group Antibodies

ReactivityHuman

TargetSMAD2

Overview

Supplier
Cusabio
Product Name
SMAD2 Antibody
Delivery Days Customer
20
Applications
ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID4087
Target name
SMAD2
Target description
SMAD family member 2
Target synonyms
hMAD-2; hSMAD2; JV18; JV18-1; MAD homolog 2; MADH2; MADR2; mother against DPP homolog 2; mothers against decapentaplegic homolog 2; Sma- and Mad-related protein 2; SMAD, mothers against DPP homolog 2
Host
Rabbit
Isotype
IgG
Protein IDQ15796
Protein Name
Mothers against decapentaplegic homolog 2
Scientific Description
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
Reactivity
Human
Storage Instruction
-20°C or -80°C
UNSPSC
12352203

SMAD2 Antibody

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Overview