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SMAD2 Monoclonal Antibody

Research Use Only
CSB-MA913719
Cusabio
ApplicationsWestern Blot, ELISA, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetSMAD2
Price on request
Packing Size
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More than 130 suppliers
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Overview

  • Supplier
    Cusabio
  • Product Name
    SMAD2 Monoclonal Antibody
  • Delivery Days Customer
    20
  • Applications
    Western Blot, ELISA, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Conjugate
    Unconjugated
  • Gene ID4087
  • Target name
    SMAD2
  • Target description
    SMAD family member 2
  • Target synonyms
    hMAD-2; hSMAD2; JV18; JV18-1; MAD homolog 2; MADH2; MADR2; mother against DPP homolog 2; mothers against decapentaplegic homolog 2; Sma- and Mad-related protein 2; SMAD, mothers against DPP homolog 2
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDQ15796
  • Protein Name
    Mothers against decapentaplegic homolog 2
  • Scientific Description
    Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases.Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and,on formation of the SMAD2/SMAD4 complex,activates transcription.May act as a tumor suppressor in colorectal carcinoma.Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203