Bio-Connect
FACS analysis of HeLa cells using GTX01034 SMAD2 (phospho Ser250) antibody [SD207-1]. Red : primary antibody Black : unlabelled control Dilution : 1:50
FACS analysis of HeLa cells using GTX01034 SMAD2 (phospho Ser250) antibody [SD207-1]. Red : primary antibody Black : unlabelled control Dilution : 1:50
FACS analysis of HeLa cells using GTX01034 SMAD2 (phospho Ser250) antibody [SD207-1]. Red : primary antibody Black : unlabelled control Dilution : 1:50

SMAD2 (phospho Ser250) antibody [SD207-1] - Recombinant antibody, Orthogonal Validated

Research Use Only
GTX01034
GeneTex
ApplicationsFlow Cytometry, Western Blot
Product group Antibodies
ReactivityHuman
TargetSMAD2
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    SMAD2 (phospho Ser250) antibody [SD207-1] - Recombinant antibody, Orthogonal Validated
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry, Western Blot
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    SD207-1
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4087
  • Target name
    SMAD2
  • Target description
    SMAD family member 2
  • Target synonyms
    hMAD-2; hSMAD2; JV18; JV18-1; MAD homolog 2; MADH2; MADR2; mother against DPP homolog 2; mothers against decapentaplegic homolog 2; Sma- and Mad-related protein 2; SMAD, mothers against DPP homolog 2
  • Host
    Rabbit
  • Isotype
    IgG
  • Modification Type
    Phosphorylated
  • Scientific Description
    The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene mothers against decapentaplegic (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203