The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA948107(SMAD4 Antibody) at dilution 1/40. (Original magnification: x200)
The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA948107(SMAD4 Antibody) at dilution 1/40. (Original magnification: x200)
SMAD4 Antibody
CSB-PA948107
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetSMAD4
Overview
- SupplierCusabio
- Product NameSMAD4 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID4089
- Target nameSMAD4
- Target descriptionSMAD family member 4
- Target synonymsdeleted in pancreatic carcinoma locus 4; deletion target in pancreatic carcinoma 4; DPC4; JIP; MAD homolog 4; MADH4; mothers against decapentaplegic homolog 4; mothers against decapentaplegic, Drosophila, homolog of, 4; MYHRS; SMAD, mothers against DPP homolog 4
- HostRabbit
- IsotypeIgG
- Protein IDQ13485
- Protein NameMothers against decapentaplegic homolog 4
- Scientific DescriptionThis gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE). The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203