SMARCA2 degrader-17

MedChem Express

SMARCA2 degrader-17

9

Research Use Only

C47H58N10O6S

891.09

SMARCA2 degrader-17 is a SMARCA2 degrader. SMARCA2 degrader-17 shows synergistic anti-proliferation effects with Adagrasib (HY-130149) in cancer cells. SMARCA2 degrader-17 inhibits tumor growth[1].

OC1=C(C=CC=C1)C2=NN=C3NC[C@](CN([C@H]4CN(CC4)C[C@H](C)OC5=NOC([C@@H](C(C)C)C(N6[C@@H](C[C@H](C6)O)C(N[C@H](C7=CC=C(C8=C(N=CS8)C)C=C7)C)=O)=O)=C5)CC9)([H])N9C3=C2

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