SMARCA2-IN-7 [2270879-43-9]

TargetMol Chemicals

SMARCA2-IN-7 [2270879-43-9]

9

Research Use Only

C11H9ClF2N4O2S

334.73

SMARCA2-IN-7 (compound 12) acts as a dual inhibitor for both BRM and BRG1 with IC50 values less than 0.005, exhibiting antitumor proliferation effects. It inhibits tumor proliferation in SKMEL5 cells lacking BRG1 with an AAC50 of 13 nM. Additionally, in H1299 cells, it suppresses cell proliferation activity of KRT880 with an AAC50 of 42 nM.

O=C(NC=1SN=C(C1)C(F)F)NC2=CC(Cl)=NC=C2CO

-20°C

51202000