SMARCB1 antibody

Biorbyt

SMARCB1 antibody

16

Western Blot

WB:1:1000-1:5000 WB

Research Use Only

Polyclonal

Unconjugated

SMARCB1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1

BAF47; BRG1-associated factor 47; CSS3; hSNF5; hSNFS; INI1; integrase interactor 1 protein; malignant rhabdoid tumor suppressor; MRD15; PPP1R144; protein phosphatase 1, regulatory subunit 144; RDT; RTPS1; Sfh1p; SNF5; SNF5 homolog; SNF5L1; Snr1; sucrose nonfermenting, yeast, homolog-like 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; SWI/SNF-related matrix-associated protein; SWNTS1

Rabbit

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

Rabbit polyclonal to SMARCB1.SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1(SMARCB1) is a nuclear protein and a core component of the BAF (hSWI/SNF) complex. This ATPdependentchromatin-remodeling complex plays important roles in cell proliferation and differentiation,cellular antiviral activities and inhibition of tumor formation. The BAF (hSWI/SNF) complex relievesrepressive chromatin structures, allowing the transcriptional machinery to access its targets moreeffectively. SMARCB1 may also bind to and enhance the DNA joining activity of HIV-1 integrase.SMARCB1 has been implicated as a tumor suppressor, and mutations in it have been associated withmalignant rhabdoid tumors.

Human

-20°C

12352203