SMARCD3 Antibody

Cusabio

SMARCD3 Antibody

20

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

SMARCD3

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3

60 kDa BRG-1/Brm-associated factor subunit C; BAF60C; BRG1-associated factor 60C; chromatin remodeling complex BAF60C subunit; CRACD3; mammalian chromatin remodeling complex BRG1-associated factor 60C; Rsc6p; SWI/SNF complex 60 kDa subunit C; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3; Swp73-like protein

Rabbit

IgG

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3

Plays a role in ATP dependent nucleosome remodeling by SMARCA4 containing complexes. Stimulates nuclear receptor mediated transcription. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).

Human, Mouse

-20°C or -80°C

41116161