ICC/IF analysis of HepG2 cells using GTX87360 SMG7 antibody. The picture on the right is blocked with the synthesized peptide.
ICC/IF analysis of HepG2 cells using GTX87360 SMG7 antibody. The picture on the right is blocked with the synthesized peptide.
SMG7 antibody
GTX87360
Overview
- SupplierGeneTex
- Product NameSMG7 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500~1:1000. ICC/IF: 1:100~1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- FormulationLiquid
- Gene ID9887
- Target nameSMG7
- Target descriptionSMG7 nonsense mediated mRNA decay factor
- Target synonymsbreast cancer-associated antigen SGA-56M; C1orf16; EST1 telomerase component homolog C; EST1C; EST1-like protein C; ever shorter telomeres 1C; protein SMG7; SGA56M; smg-7 homolog, nonsense mediated mRNA decay factor
- Protein IDQ92540
- Protein NameProtein SMG7
- Scientific DescriptionThis gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD); a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2011]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203