ICC/IF analysis of HepG2 cells using GTX87360 SMG7 antibody. The picture on the right is blocked with the synthesized peptide.
ICC/IF analysis of HepG2 cells using GTX87360 SMG7 antibody. The picture on the right is blocked with the synthesized peptide.
SMG7 antibody
GTX87360
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetSMG7
Overview
- SupplierGeneTex
- Product NameSMG7 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500~1:1000. ICC/IF: 1:100~1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID9887
- Target nameSMG7
- Target descriptionSMG7 nonsense mediated mRNA decay factor
- Target synonymsbreast cancer-associated antigen SGA-56M; C1orf16; EST1 telomerase component homolog C; EST1C; EST1-like protein C; ever shorter telomeres 1C; protein SMG7; SGA56M; smg-7 homolog, nonsense mediated mRNA decay factor
- HostRabbit
- IsotypeIgG
- Protein IDQ92540
- Protein NameProtein SMG7
- Scientific DescriptionThis gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD); a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2011]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203