Immunohistochemistry of paraffin-embedded Human colon cancer tissue using SMG8 Polyclonal Antibody at dilution 1:50
SMG8 Polyclonal Antibody
E-AB-12757
Product group Antibodies
Overview
- SupplierElabscience
- Product NameSMG8 Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA IHC
- CertificationResearch Use Only
- Concentration0.3mg/ml
- Scientific DescriptionInvolved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity.
- UNSPSC12352203