SMYD2 Antibody, HRP conjugated

Cusabio

SMYD2 Antibody, HRP conjugated

20

ELISA

Research Use Only

Polyclonal

HRP

SMYD2

SET and MYND domain containing 2

histone methyltransferase SMYD2; HSKM-B; KMT3C; lysine N-methyltransferase 3C; N-lysine methyltransferase SMYD2; SET and MYND domain-containing protein 2; zinc finger, MYND domain containing 14; ZMYND14

Rabbit

IgG

N-lysine methyltransferase SMYD2

Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 \\\Lys-4\\\ (H3K4me) and dimethylates histone H3 \\\Lys-36\\\ (H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates \\\Lys-370\\\ of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at \\\Lys-860\\\.

Human

-20°C or -80°C

12352203