SN-38-d3

MedChem Express

SN-38-d3 [718612-49-8]

10

718612-49-8

Research Use Only

99.07

C22H17D3N2O5

395.42

SN-38-d 3 is the deuterium labeled SN-38. SN-38 (NK012) is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 (NK012) inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 microM, respectively[1][2][3][4].

[2H]C([2H])([2H])CC1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)CC)=C4C3=O)=NC5=CC=C(O)C=C51

-20°C

12352200