SNAP25 antibody
GTX113839
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat, Zebra Fish
TargetSNAP25
Overview
- SupplierGeneTex
- Product NameSNAP25 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.27 mg/ml
- ConjugateUnconjugated
- Gene ID6616
- Target nameSNAP25
- Target descriptionsynaptosome associated protein 25
- Target synonymsbA416N4.2; CMS18; dJ1068F16.2; resistance to inhibitors of cholinesterase 4 homolog; RIC4; RIC-4; SEC9; SNAP; SNAP-25; SUP; synaptosomal-associated protein 25; synaptosomal-associated protein, 25kDa; synaptosome associated protein 25kDa
- HostRabbit
- IsotypeIgG
- Protein IDP60880
- Protein NameSynaptosomal-associated protein 25
- Scientific DescriptionSynaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat, Zebra Fish
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Activation of alpha7 Nicotinic Acetylcholine Receptor by its Selective Agonist Improved Learning and Memory of Amyloid Precursor Protein/Presenilin 1 (APP/PS1) Mice via the Nrf2/HO-1 Pathway. Cao K et al., 2022 Jan 4, Med Sci MonitRead more
- Sinoatrial node pacemaker cells share dominant biological properties with glutamatergic neurons. Liang D et al., 2021 Jul, Protein CellRead more
- Blood-Brain Barrier Disruption Increases Amyloid-Related Pathology in TgSwDI Mice. Abdallah IM et al., 2021 Jan 27, Int J Mol SciRead more
- Lowered levels of nicotinic acetylcholine receptors and elevated apoptosis in the hippocampus of brains from patients with type 2 diabetes mellitus and db/db mice. Xu Y et al., 2020 Jul 23, Aging (Albany NY)Read more
- The neuroprotective effects of SIRT1 in mice carrying the APP/PS1 double-transgenic mutation and in SH-SY5Y cells over-expressing human APP670/671 may involve elevated levels of alpha7 nicotinic acetylcholine receptors. Cao K et al., 2020 Jan 30, Aging (Albany NY)Read more
- Activation of alpha7 nAChR by PNU-282987 improves synaptic and cognitive functions through restoring the expression of synaptic-associated proteins and the CaM-CaMKII-CREB signaling pathway. Wang XL et al., 2020 Jan 6, Aging (Albany NY)Read more
- Granisetron Alleviates Alzheimers Disease Pathology in TgSwDI Mice Through Calmodulin-Dependent Protein Kinase II/cAMP-Response Element Binding Protein Pathway. Al Rihani SB et al., 2019, J Alzheimers DisRead more
- Exposure to fluoride aggravates the impairment in learning and memory and neuropathological lesions in mice carrying the APP/PS1 double-transgenic mutation. Cao K et al., 2019 Apr 22, Alzheimers Res TherRead more
- Plasma Rich in Growth Factors (PRGF) Disrupt the Blood-Brain Barrier Integrity and Elevate Amyloid Pathology in the Brains of 5XFAD Mice. Duong QV et al., 2019 Mar 25, Int J Mol SciRead more
- Multi-faceted therapeutic strategy for treatment of Alzheimers disease by concurrent administration of etodolac and alpha-tocopherol. Elfakhri KH et al., 2019 May, Neurobiol DisRead more