Bio-Connect

SNX27 Antibody, HRP conjugated

Research Use Only
CSB-PA842704LB01HU
Cusabio
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetSNX27
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Cusabio
  • Product Name
    SNX27 Antibody, HRP conjugated
  • Delivery Days Customer
    20
  • Applications
    ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    HRP
  • Gene ID81609
  • Target name
    SNX27
  • Target description
    sorting nexin 27
  • Target synonyms
    methamphetamine-responsive transcript 1; MRT1; MY014; sorting nexin family member 27; sorting nexin-27
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ96L92
  • Protein Name
    Sorting nexin-27
  • Scientific Description
    Involved in the retrograde transport from endosome to plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins. Following internalization, endocytosed transmembrane proteins are delivered to early endosomes and recycled to the plasma membrane instead of being degraded in lysosomes. SNX27 specifically binds and directs sorting of a subset of transmembrane proteins containing a PDZ-binding motif at the C-terminus: following interaction with target transmembrane proteins, associates with the retromer complex, preventing entry into the lysosomal pathway, and promotes retromer-tubule based plasma membrane recycling. SNX27 also binds with the WASH complex. Interacts with membranes containing phosphatidylinositol-3-phosphate (PtdIns(3P)). May participate in establishment of natural killer cell polarity. Recruits CYTIP to early endosomes.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203