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SOCS3 Polyclonal Antibody

Research Use Only
RD80136A
Reddot Biotech
ApplicationsWestern Blot
Product group Antibodies
ReactivityMouse, Rat
TargetSOCS3
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    SOCS3 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID9021
  • Target name
    SOCS3
  • Target description
    suppressor of cytokine signaling 3
  • Target synonyms
    ATOD4; CIS3; Cish3; cytokine-inducible SH2 protein 3; SOCS-3; SSI3; SSI-3; STAT-induced STAT inhibitor 3; suppressor of cytokine signaling 3
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.
  • Reactivity
    Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203