SOCS3 Polyclonal Antibody
RD80136A
ApplicationsWestern Blot
Product group Antibodies
ReactivityMouse, Rat
TargetSOCS3
Overview
- SupplierReddot Biotech
- Product NameSOCS3 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID9021
- Target nameSOCS3
- Target descriptionsuppressor of cytokine signaling 3
- Target synonymsATOD4; CIS3; Cish3; cytokine-inducible SH2 protein 3; SOCS-3; SSI3; SSI-3; STAT-induced STAT inhibitor 3; suppressor of cytokine signaling 3
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.
- ReactivityMouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203