Western blot All lanes: SOCS5 antibody IgG at 1.83ug/ml + 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 61 kDa Observed band size: 61 kDa
Western blot All lanes: SOCS5 antibody IgG at 1.83ug/ml + 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 61 kDa Observed band size: 61 kDa
SOCS5 Antibody
CSB-PA022394ESR2HU
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetSOCS5
Overview
- SupplierCusabio
- Product NameSOCS5 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID9655
- Target nameSOCS5
- Target descriptionsuppressor of cytokine signaling 5
- Target synonymsCIS6; CIS-6; Cish5; CISH6; cytokine-inducible SH2 protein 6; cytokine-inducible SH2-containing protein 5; SOCS-5; suppressor of cytokine signaling 5
- HostRabbit
- IsotypeIgG
- Protein IDO75159
- Protein NameSuppressor of cytokine signaling 5
- Scientific DescriptionSOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits for instance EGF signaling by mediating the degradation of the EGF receptor/EGFR. Involved in the regulation of T-helper cell differentiation by inhibiting of the IL4 signaling pathway which promotes differentiation into the Th2 phenotype. Can also partially inhibit IL6 and LIF signaling.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203