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IHC-P analysis of human colon carcinoma tissue using GTX22873 Sodium/Potassium ATPase beta 1 antibody [M17-P5-F11]. Left : Primary antibody Right : Negative control without primary antibody Antigen retrieval : heat induced antigen retrieval was performed using 10mM sodium citrate (pH6.0) buffer, microwaved for 8-15 minutes Dilution : 1:200
IHC-P analysis of human colon carcinoma tissue using GTX22873 Sodium/Potassium ATPase beta 1 antibody [M17-P5-F11]. Left : Primary antibody Right : Negative control without primary antibody Antigen retrieval : heat induced antigen retrieval was performed using 10mM sodium citrate (pH6.0) buffer, microwaved for 8-15 minutes Dilution : 1:200
IHC-P analysis of human colon carcinoma tissue using GTX22873 Sodium/Potassium ATPase beta 1 antibody [M17-P5-F11]. Left : Primary antibody Right : Negative control without primary antibody Antigen retrieval : heat induced antigen retrieval was performed using 10mM sodium citrate (pH6.0) buffer, microwaved for 8-15 minutes Dilution : 1:200

Sodium/Potassium ATPase beta 1 antibody [M17-P5-F11]

GTX22873
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetATP1B1
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Overview

  • Supplier
    GeneTex
  • Product Name
    Sodium/Potassium ATPase beta 1 antibody [M17-P5-F11]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:10,000. ICC/IF: 1:100-1:1000. IHC-P: 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    M17-P5-F11
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID481
  • Target name
    ATP1B1
  • Target description
    ATPase Na+/K+ transporting subunit beta 1
  • Target synonyms
    ATP1B, sodium/potassium-transporting ATPase subunit beta-1, ATPase, Na+/K+ transporting, beta 1 polypeptide, Beta 1-subunit of Na(+),K(+)-ATPase, Na, K-ATPase beta-1 polypeptide, adenosinetriphosphatase, sodium pump subunit beta-1, sodium-potassium ATPase subunit beta 1 (non-catalytic), sodium/potassium-dependent ATPase beta-1 subunit, sodium/potassium-transporting ATPase beta-1 chain
  • Host
    Mouse
  • Isotype
    IgG2a
  • Protein IDP05026
  • Protein Name
    Sodium/potassium-transporting ATPase subunit beta-1
  • Scientific Description
    The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known. [provided by RefSeq, Mar 2010]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Dystrophin Threshold Level Necessary for Normalization of Neuronal Nitric Oxide Synthase, Inducible Nitric Oxide Synthase, and Ryanodine Receptor-Calcium Release Channel Type 1 Nitrosylation in Golden Retriever Muscular Dystrophy Dystrophinopathy. Gentil C et al., 2016 Sep, Hum Gene Ther
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  • Sodium channels contribute to degeneration of dorsal root ganglion neurites induced by mitochondrial dysfunction in an in vitro model of axonal injury. Persson AK et al., 2013 Dec 4, J Neurosci
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