SOS1-IN-14

MedChem Express

SOS1-IN-14

10

Research Use Only

99.60

C29H29F3N6O2

550.57

SOS1-IN-14 is a potent, selective and orally active SOS1 inhibitor with an IC 50 value of 3.9 nM. SOS1-IN-14 can be absorbed in the intestine via a P-glycoprotein-mediated efflux mechanism. SOS1-IN-14 can be used to research KRAS-mutated cancers. SOS1-IN-14 has better potent tumor suppression than BI-3406 (HY-125817) [1] .

N#CC1(C(N2C[C@]3([H])CCOC4=CC5=NC(C)=NC(N[C@@H](C6=CC=CC(C(F)F)=C6F)C)=C5C=C4N3CC2)=O)CC1

-20°C

12352200