Bio-Connect

SOST Polyclonal Antibody

RD267962A
Reddot Biotech
ApplicationsImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetSOST
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    SOST Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID50964
  • Target name
    SOST
  • Target description
    sclerostin
  • Target synonyms
    CDD; DAND6; sclerostin; SOST1; VBCH
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203