SOST Polyclonal Antibody
RD267962A
ApplicationsImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetSOST
Overview
- SupplierReddot Biotech
- Product NameSOST Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoHistoChemistry
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID50964
- Target nameSOST
- Target descriptionsclerostin
- Target synonymsCDD; DAND6; sclerostin; SOST1; VBCH
- HostRabbit
- IsotypeIgG
- Scientific DescriptionSclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203