Sotorasib

BPS Bioscience

Sotorasib [2296729-00-3]

23

Research Use Only

≥90%

Sotorasib (AMG-510) is a first-in-class, orally bioavailable, and selective KRAS G12C covalent inhibitor. Sotorasib irreversibly inhibits KRAS G12C by locking it in an inactive GDP-bound state. Sotorasib is the first KRAS G12C inhibitor in clinical development and leads to the regression of KRAS G12C tumors1,2.

-20°C,-80°C

51202000