Sp-cAMPS

MedChem Express

Sp-cAMPS

10

71774-13-5

C10H12N5O5PS

345.27

Sp-cAMPS, a cAMP analog, is potent activator of cAMP-dependent PKA I and PKA II . Sp-cAMPS is also a potent, competitive phosphodiesterase (PDE3A) inhibitor with a K i of 47.6 microM. Sp-cAMPS binds the PDE10 GAF domain with an EC 50 of 40 microM [1] [2] [3] .

O[C@H]1[C@@H](O[C@@]2([H])[C@@]1([H])O[P@](OC2)(S)=O)N3C4=C(C(N)=NC=N4)N=C3

12352200